[Exclusively based parenteral fish-oil emulsion (Omegaven®) in the treatment of parenteral nutrition associated liver disease: Report of a case].
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چکیده
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منابع مشابه
Use of parenteral fish oil to reverse cholestasis induced by parenteral nutrition in infants with intestinal failure: single-centre case series.
Published data assessing the efficacy and toxicity of omega-3 fatty acid emulsion in children are limited. Until recently, children requiring long-term parenteral nutrition who experienced parenteral nutrition–associated liver disease (PNALD) were likely to die from infection or liver disease before receiving a small bowel and/or liver transplant. With the introduction of parenteral fish oil (1...
متن کاملAnti-Inflammatory and Anti-Fibrotic Profile of Fish Oil Emulsions Used in Parenteral Nutrition-Associated Liver Disease
Home parenteral nutrition (PN) is associated with many complications including severe hepatobiliary dysfunction. Commercial ω-6 fatty acid-soybean based-lipid emulsions in PN may mediate long term PN associate liver disease (PNALD) whereas ω-3-fish oil parenteral emulsions have shown to reverse PNALD in children. However, its clinical effectiveness in adults has been scarcely reported. In this ...
متن کاملLipid emulsions in the treatment and prevention of parenteral nutrition-associated liver disease in infants and children.
Long-term parenteral nutrition (PN) carries the risk of progressive liver disease in infants with intestinal failure. Although PN-associated liver disease (PNALD) is multifactorial in etiology, components of soybean oil lipid emulsions have been implicated in the disease's pathogenesis. Historically, infants with PNALD who were unable to wean from PN to full enteral feeding developed cirrhosis ...
متن کاملAn exclusively based parenteral fish-oil emulsion reverses cholestasis.
Prolonged parenteral nutrition (PN) leads to liver damage. Recent interest has focused on the lipid component of PN. A lipid emulsion based on w-3 fatty acids decrease conjugated bilirubin. A mixed lipid emulsion derived from soybean, coconut, olive, and fish oils reverses jaundice. Here we report the reversal of cholestasis and the improvement of enteral feeding tolerance in 1 infant with inte...
متن کاملLipid emulsions in the treatment and prevention of parenteral nutrition–associated liver disease in infants and children123
Long-term parenteral nutrition (PN) carries the risk of progressive liver disease in infants with intestinal failure. Although PN-associated liver disease (PNALD) is multifactorial in etiology, components of soybean oil lipid emulsions have been implicated in the disease’s pathogenesis. Historically, infants with PNALD who were unable to wean from PN to full enteral feeding developed cirrhosis ...
متن کاملSafety and efficacy of a fish-oil-based fat emulsion in the treatment of parenteral nutrition-associated liver disease.
BACKGROUND Parenteral nutrition-associated liver disease can be a progressive and fatal entity in children with short-bowel syndrome. Soybean-fat emulsions provided as part of standard parenteral nutrition may contribute to its pathophysiology. METHODS We compared safety and efficacy outcomes of a fish-oil-based fat emulsion in 18 infants with short-bowel syndrome who developed cholestasis (s...
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ورودعنوان ژورنال:
- Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion
دوره 62 6 شماره
صفحات -
تاریخ انتشار 2015